Ph.375 isn’t the catchiest name for a supplement, but with its formula of eight different active ingredients, it certainly shows promise. The company state it does everything from help you lose weight to increase your mood which sounds perfect. What does it do though and has it been proven to work? We’ll look at the ingredients and science behind them and if this supplement can really help you lose weight.
Artichoke Leaf Extract
Artichoke is a common vegetable in Mediterranean diets and has been used as both food and medicine for thousands of years. It’s well known as a traditional medicine for many liver-related illnesses like jaundice and even GI problems. These abilities have both been proven clinically.
The manufacturer claims the artichoke extract is supposed to make you feel fuller and decrease your hunger. However, there is no proof of this in clinical studies.
What Artichoke Leaf Extract is proven to do in clinical trials is reduce cholesterol in otherwise healthy people and even reduce further absorption of cholesterol although those trials were still in the rodent testing stage. It’s also proven to promote a healthy gut and have other effects on the digestive system. Artichoke is a probiotic which restores the natural balance of bacteria in the stomach.
Cayenne Pepper is there to reduce your metabolism, increase your body temperature and reduce food cravings.
The active ingredient in cayenne pepper is capsaicin which has long been used as an analgesic and is a clinically proven painkiller. It’s commonly available as a cream and often used to treat arthritis and studies in animals showed it did the same when taken orally.
Of course in this supplement, that’s not what you’re taking it for. One study has shown that cayenne pepper does indeed decrease appetite. However, the amounts needed are very large (up to ten grams), and there are few other studies of capsaicin due to its taste and burning effect on the mouth. Another study also proved that capsaicin does, in fact, increase your body temperature and thus aids in burning calories.
Calcium Carbonate is a mineral that is commonly used to improve the bone health of millions of people. It’s also an ingredient in many antacids and indigestion remedies available over the counter. As a weight loss aid, clinical trials have proved that those on a reduced calorie diet and taking a calcium supplement increased the weight loss of the participants. A low-fat but high dairy can also have the same effects.
Chromium is a mineral found in many foods and often paired with picolinate to help the body absorb the mineral more easily. While chromium deficiency is rare as humans only need a trace amount of this mineral in their bodies.
One use is the regulation of blood sugar levels in people with diabetes which may be of use to those losing weight. However, trials have shown that it is not necessarily the case and most studies have been inconclusive and have shown that there is no effect in those without diabetes.
Studies have shown that Chromium Picolinate can reduce cholesterol levels in people with high cholesterol. A dose of between 15 to 200 mcg over the course of six to twelve weeks reduced the amount of lipoprotein – the bad cholesterol in your body in the study sample. This is something that worked better for those participants who already had high cholesterol.
L-Carnitine is an amino acid found in the body and part of what makes up the protein. It’s important for heart function and muscle movement and as a supplement only usually used on those who are deficient in L-Catinine due to genetic disorders or because they’re taking a certain type of medication. Vegans and Vegetarians also benefit from taking L-Carnitine supplements as most of the body’s natural intake of this amino acid come from red meat, dairy and chicken.
In this weight loss supplement, L-Carnitine is a fat burner, reducing fatigue and improving muscle mass. Quality studies have proved this to be the case in elderly patients. Fewer studies have been done on young men or woman, and ones that were performed showed no weight loss and a minimal decrease in fatigue.
Citrus Aurantium Extract
This extract is made from oranges and is better known as ‘bitter orange.’ It can be made from the peal, leaves or the fruit itself though bitter orange oil is made from the peel. The oil has been used for a long time for different skin conditions, though the only clinically proven study has been the use of the extract to treat fungal infections.
Other studies into the weight loss attributes of Citrus Aurantium show promising results in weight loss when paired with caffeine (which in this supplement it is) and other compounds. More studies need to be done on humans as most of the studies so far have been done on rats.
Caffeine is a stimulant that most people will regularly be taking. Whether it’s in your morning coffee or an afternoon’s cold soda, you’ve probably had some caffeine today. There are many myths about the detrimental effects caffeine can have on a person’s health, but it actually has many health benefits.
Caffeine is clinically proven to reduce feelings of fatigue and drowsiness which can be a common side effect of the dieting process. It also a performance enhancer and stimulates the body into generating energy and heat from food, even when you are at rest. This means it’s going to aid in digestion and energy production whether you’re exercising or not. It’s also thought to be an appetite suppressant, but clinical studies into this, and caffeine as a weight loss aid are of too low a quality to be definitive.
This ingredient is also more commonly known as Forskolin and is widely used as a weight loss supplement. Forskolin is from a plant in the mint family – the Coleus Forskohlii. It’s been used for hundreds of years as a traditional medicine, most notable as a remedy for asthma and glaucoma. More recently studies have been performed to see if it is effective as a weight loss aid.
Studies have shown some minor weight loss, by breaking down fat in the body and excreting; rather than storing it. This means it also prevents weight gain and the studies showed that it is more effective in men than in women.
Ph.375 Side Effects
With so many different active ingredients there are bound to be plenty of side effects that you need to be aware of. As with every supplement, you should consult with your pharmacist or doctor before starting, especially if you’re on any prescription medication, pregnant or breastfeeding.
Most of the ingredients are perfectly safe to take as they are already found in the body, such as the calcium, chromium and L-Catlinite. The latter two substances do not have any recorded side effects at all. Higher doses of calcium can be dangerous, but in those amounts, you would have to take multiple high dose supplements which is never safe to do. The side effect most common to calcium is constipation.
Unfortunately, this is a side effect of caffeine too but something that can be dealt with by using over the counter remedies. However, you should always seek medical advice if you are concerned about any medical problems – such as dark stools or blood in your stools.
Other ingredients in Ph.375 have negative effects on the stomach. These include upset stomachs or stomach irritation (uncomfortable stomach ache) gas. These will be more common in people who already have gastrointestinal problems and those who do not regularly use cayenne pepper (or other capsaicin containing peppers) in their diets. However, the stomach can and will adapt to this.
Many of the ingredients have contradicting side effects; where the calcium and caffeine cause constipation, the artichoke leaf extract can cause diarrhea. This laxative effect of the leaf should negate the effects the calcium and caffeine have. The same goes for the effects of the Citrus and Caffeine on blood pressure. Whereas those two ingredients can increase your blood pressure, Forskolin lowers blood pressure. This doesn’t mean it will rise then fall, and you will feel the effects of a change in blood pressure (headaches, dizziness, etc.), but in fact, little to nothing should happen to your blood pressure as they are all working in conjunction.
Other side effects of Ph.375 can include all the physical side effects of eating too much chili pepper such as flushing, sweating and watery eyes – again only if you’re not used to pepper is this going to happen. It can also cause increased heartbeat, fainting spells (due to changes in blood pressure) and if taken later in the evening or at night then the caffeine in this product is going to cause some sleeplessness. The side effects of the Citrus Aurantium Extract are increased when taken with caffeine, and it’s important to only take the recommended dose and no more to decrease any risk when taking this product.
Ph.375 is safe to take for most people who are not already taking medication – following the directions and never taking more than the recommended dose is always the safest way to take any supplement. Taking more to lose weight faster will put your health at greater risk and not likely to speed up any weight loss. Some of the ingredients also interact with blood thinning medication, and this includes aspirin so checking with your pharmacist or doctor is advisable.
Ph.375 Customer Reviews & Results
The reviews we were able to find online by actual users of Ph.375 are positive with successful weight loss. People have lost 8lbs in a week and up to 24lbs in three months. These are some incredible results, but we have found that many of these testimonials all come from the same source – the Ph.375 website. Preferably user reviews would be independent of the manufacturer, and we rate impartial reviews as a much better way to judge whether supplements are having positive effects on dieters.
- Natural ingredients
- Multiple active ingredients
- Clinically proven
Many of the active ingredients in Ph.375 are natural and already occur naturally in the body. Caffeine is so ubiquitous in our every day lives that it feels natural to many of us. However, when taking this supplement, it may be worth cutting back on your regular caffeine intake as to not overdo it.
With so many active ingredients there is a lot of promise in this supplement. Ph.375 have taken the best of what’s out there and put them together, so you just have to take one supplement instead of two or three to get the most effective weight loss. On top of that, many of the active ingredients have clinical trials to back up the claims made by Ph.375.
- Some studies of low quality or on rodents only
- Many Side effects
While many studies prove that this supplement aids in weight loss, but not as a fat burner. Clinical trials indicate this supplement will reduce cholesterol, decrease fatigue and improve performance during exercise and have some effect on appetite. However, trials into actual fat burning or preventing further weight gain are of low quality or have only been performed on rodents so far and have not reached the human testing stage.
Another negative factor for this supplement is the price. For also $70 you only get 30 tablets which is a lot for something that may not work for you. However, if you are serious about losing weight, plan to diet and exercise and need an extra boost then the cost is worth it.
Conclusion & Recommendation
There is a lot of good things about this supplement that makes it worth the money and worth adding to your weight loss regime. While the lack of impartial user reviews does throw some doubt on the effectiveness of the product, you can’t ignore the successful clinical trials and the eight fantastic active ingredients. It will boost energy levels and lower fatigue thanks to the caffeine.
The natural ingredients have a lot of great benefits beyond those affecting weight loss that will be good for anyone who wants to improve their health as much as possible beyond just losing weight. While it may not be a miracle supplement, none are, you get a lot of help with Ph.375 beyond just a tablet. You get a nutrition guide, work out guide and more to help you lose weight and keep the weight off. Add a sixty-day money back guarantee and Ph.375 becomes a very attractive prospect we would definitely try.